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Study protocol randomised controlled trial evaluating exercise therapy as a supplemental treatment strategy in early multiple sclerosis the Early Multiple Sclerosis Exercise Study (EMSES)

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Abstract Introduction In the relapsing remitting type of multiple sclerosis (MS) reducing relapses and neurodegeneration is crucial in halting the long-term impact of the disease. Medical disease-modifying treatments have proven effective, especially when introduced early in the disease course. However, patients still experience disease activity and disability progression, and therefore, supplemental early treatment strategies are […]

Efficacy and safety of oxygen-sparing nasal reservoir cannula for treatment of pediatric hypoxemic pneumonia in Uganda: a pilot randomized clinical trial

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Abstract Background: Oxygen is an essential therapy for hypoxemia but is scarce in low-income settings. Oxygen conserving devices optimize delivery, but to date have been designed for adults in high-income settings. Here we present the development and clinical pilot study of an oxygen-sparing nasal reservoir cannula (OSNRC) for pediatric use in low-income settings. Methods (1) […]

Watch the Thornhill Medical COVID-19 response in action

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Oxigraf is proud of supporting the Thornhill Medical COVID-19 Response Action Plan! Thornhill Medical is answering the call to support the fight against COVID-19, producing and delivering the MOVES® SLC™ devices to help save lives across the country. Combining an O₂ concentrator, ventilator, suction & vital signs monitoring in a rugged battery-powered portable unit, MOVES® […]

2020 Holiday Schedule Update

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Oxigraf Offices will be closed the following days during the 2020 holiday season: December 25, 2020 Closed for Christmas; January 1, 2021 Closed for New Years Day

CMTC welcomes Oxigraf to the Made in California Program!

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Oxigraf is now part of the Made in California Program, California’s trusted resource for a thriving manufacturing industry. Made in California is dedicated to highlighting the contributions of California’s manufacturers and raising awareness of the products made in the Golden State. Oxigraf is proud of contributing to the success of keeping manufacturing in California. CMTC […]

NASA’s SpaceX Crew-1 Astronauts Headed to International Space Station

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An international crew of astronauts is en route to the International Space Station following a successful launch on the first NASA-certified commercial human spacecraft system in history. NASA’s SpaceX Crew-1 mission lifted off at 7:27 p.m. EST Sunday from Launch Complex 39A at the agency’s Kennedy Space Center in Florida. The SpaceX Falcon 9 rocket […]

Neuronal adenosine A2A receptors signal ergogenic effects of caffeine

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Abstract Caffeine is one of the most used ergogenic aid for physical exercise and sports. However, its mechanism of action is still controversial. The adenosinergic hypothesis is promising due to the pharmacology of caffeine, a nonselective antagonist of adenosine A1 and A2A receptors. We now investigated A2AR as a possible ergogenic mechanism through pharmacological and genetic inactivation. […]

Frontal and motor cortex oxygenation during maximal exercise in normoxia and hypoxia

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Abstract Reductions in prefrontal oxygenation near maximal exertion may limit exercise performance by impairing executive functions that influence the decision to stop exercising; however, whether deoxygenation also occurs in motor regions that more directly affect central motor drive is unknown. Multichannel near-infrared spectroscopy was used to compare changes in prefrontal, premotor, and motor cortices during […]

Oxigraf White Paper

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Quantum Computer Helium Laboratory Oxygen Deficiency Monitor O2iM from Oxigraf: Application Note in the September Issue of Spectroscopy Magazine (pdf)