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A Device for the Quantification of Oxygen Consumption and Caloric Expenditure in the Neonatal Range

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BACKGROUND: The accurate measurement of oxygen consumption (VO2) and energy expenditure (EE) may be helpful to optimize the treatment of critically ill patients. However, current techniques are limited in their ability to accurately quantify these end points in infants due to a low VO2, low tidal volume, and rapid respiratory rate. This study describes and […]

World Health Day

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Today is World Health Day, and we want to say to every healthcare worker in the medical field who helps keep us healthy: Thank you for everything you do, you are loved and appreciated!

System Design Verification for Closed Loop Control of Oxygenation With Concentrator Integration

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Abstract BACKGROUND: Addition of an oxygen concentrator into a control loop furthers previous work in autonomous control of oxygenation. Software integrates concentrator and ventilator function from a single control point, ensuring maximum efficiency by placing a pulse of oxygen at the beginning of the breath. We sought to verify this system. Methods: In a test […]

Physiorack: An integrated MRI safe/conditional, Gas delivery, respiratory gating, and subject monitoring solution for structural and functional assessments of pulmonary function

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Abstract Purpose To evaluate the use of a modular MRI conditional respiratory monitoring and gating solution, designed to facilitate proper monitoring of subjects’ vital signals and their respiratory efforts, during free‐breathing and breathheld 19F, oxygen‐enhanced, and Fourier‐decomposition MRI‐based acquisitions.   Materials and Methods All Imaging was performed on a Siemens TIM Trio 3 Tesla MRI scanner, […]

A novel, noninvasive assay shows that distal airway oxygen tension is low in cystic fibrosis, but not in primary ciliary dyskinesia

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Abstract Objectives Oxygen tension affects the biology of aerobic and denitrifying organisms. Using a novel, fast‐response sensor, we developed a noninvasive procedure to measure pO2 in distal human airways. We hypothesized that distal pO2 would be low in cystic fibrosis (CF) airways. Materials and Methods We measured the fraction of expired oxygen (FEO2) in real time using […]

Mechanical ventilators in the hot zone: Effects of a CBRN filter on patient protection and battery life

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Abstract Objective In a contaminated environment, respiratory protection for ventilator dependent patients can be achieved by attaching a chemical, biological, radiological, or nuclear (CBRN) filter to the air intake port of a portable ventilator. We evaluated the effect of the filter on battery performance of four portable ventilators in a laboratory setting. Methods Each ventilator […]

Oxygen/CO2 Analyzer for Capnography

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Model O2Cap Oxygen/CO2 Analyzer for Capnography: Monitoring of the concentration or partial pressure of oxygen and carbon dioxide (CO2) in respiratory gases requires fast response without overshoot. The Oxigraf Oxygen/CO2 Analyzers respond in less than a second. Electrochemical sensors may incorporate long averaging times, 20 or more seconds, for large, abrupt changes in oxygen concentration. […]