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System Design Verification for Closed Loop Control of Oxygenation With Concentrator Integration

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Abstract BACKGROUND: Addition of an oxygen concentrator into a control loop furthers previous work in autonomous control of oxygenation. Software integrates concentrator and ventilator function from a single control point, ensuring maximum efficiency by placing a pulse of oxygen at the beginning of the breath. We sought to verify this system. Methods: In a test […]

Physiorack: An integrated MRI safe/conditional, Gas delivery, respiratory gating, and subject monitoring solution for structural and functional assessments of pulmonary function

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Abstract Purpose To evaluate the use of a modular MRI conditional respiratory monitoring and gating solution, designed to facilitate proper monitoring of subjects’ vital signals and their respiratory efforts, during free‐breathing and breathheld 19F, oxygen‐enhanced, and Fourier‐decomposition MRI‐based acquisitions.   Materials and Methods All Imaging was performed on a Siemens TIM Trio 3 Tesla MRI scanner, […]

A novel, noninvasive assay shows that distal airway oxygen tension is low in cystic fibrosis, but not in primary ciliary dyskinesia

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Abstract Objectives Oxygen tension affects the biology of aerobic and denitrifying organisms. Using a novel, fast‐response sensor, we developed a noninvasive procedure to measure pO2 in distal human airways. We hypothesized that distal pO2 would be low in cystic fibrosis (CF) airways. Materials and Methods We measured the fraction of expired oxygen (FEO2) in real time using […]

Mechanical ventilators in the hot zone: Effects of a CBRN filter on patient protection and battery life

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Abstract Objective In a contaminated environment, respiratory protection for ventilator dependent patients can be achieved by attaching a chemical, biological, radiological, or nuclear (CBRN) filter to the air intake port of a portable ventilator. We evaluated the effect of the filter on battery performance of four portable ventilators in a laboratory setting. Methods Each ventilator […]

Oxygen/CO2 Analyzer for Capnography

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Model O2Cap Oxygen/CO2 Analyzer for Capnography: Monitoring of the concentration or partial pressure of oxygen and carbon dioxide (CO2) in respiratory gases requires fast response without overshoot. The Oxigraf Oxygen/CO2 Analyzers respond in less than a second. Electrochemical sensors may incorporate long averaging times, 20 or more seconds, for large, abrupt changes in oxygen concentration. […]

CPET – Cardiopulmonary Exercise Testing

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A cardiopulmonary exercise test (CPET) is an evaluation of the cardiopulmonary system. Physical exercise requires the interaction of the physiologic mechanisms that enable the cardiovascular and respiratory systems to support the energy demands of the contracting muscles.  Both systems are consequently stressed during exercise. Their ability to respond adequately to this stress is a measure […]

OBOGS Monitoring

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Aircrew hypoxia warning times can be reduced by perfecting laser diode absorption spectroscopy oxygen sensors for OBOGS monitoring.     The onboard oxygen generating system(OBOGS) is an alternative to liquid oxygen (LOX). When compared to a LOX system, the OBOGS has several advantages. First, it’s availability may be as high as 99 percent. There is no […]

Oxygen Depletion Calculator

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The calculation of percentage of oxygen in the air after the evaporation of a volume of liquefied gas – nitrogen or solid CO2 in a confined space. Calculate the volume (Vr m3) of the confined space. Calculate the volume of the released gas (Vg) by multiplying the volume of the liquid nitrogen (in liters) or […]